Ras-related protein Rab24 plays a predictive role in hepatocellular carcinoma and enhanced tumor proliferation

Table 3 Cox regression analysis for independent prognostic factors of hepatocellular carcinoma

Variables	HR	95%CI	P value
Serum AFP (> 400 ng/mL vs ≤ 400 ng/mL)	1.565	0.641-3.820	0.325
Tumor number (≥ 2 vs 1)	1.377	0.639-2.969	0.414
Tumor size (> 3.0 cm vs ≤ 3.0 cm)	1.048	0.558-1.967	0.884
BCLC stage (B-C vs A)	2.543	1.313-4.923	0.006
Microvascular invasion (present vs absent)	4.239	2.005-8.962	< 0.001
Resection margin (> 1.0 cm vs ≤ 1.0 cm)	2.439	1.318-4.514	0.005
Treatment (surgery vs surgery + chemotherapy)	2.950	1.646-5.286	< 0.001
Rab24 protein level (high vs low)	2.115	1.067-4.190	0.032

HR: Hazard ratio; AFP: Alpha-fetoprotein; BCLC: Barcelona Clinic Liver Cancer.