Glial cell line-derived neurotrophic factor improves impaired colonic motility in experimental colitis mice through connexin 43

Figure 3 Dextran sodium sulfate-induced ulcerative colitis mice. A: Glial cell line-derived neurotrophic factor improves colonic transit time in dextran sodium sulfate-induced ulcerative colitis mice. The colonic transit time in mice across different groups; B: Relative mRNA expression of connexin 43 in the colon of dextran sodium sulfate-induced ulcerative colitis mice in different groups; C: Relative mRNA expression of glial cell line-derived neurotrophic factor in the colon of dextran sodium sulfate-induced ulcerative colitis mice in different groups. ^bP < 0.01. GDNF: Glial cell line-derived neurotrophic factor; UC: Ulcerative colitis; CN: Normal control; Cx43: Connexin 43.