Glial cell line-derived neurotrophic factor improves impaired colonic motility in experimental colitis mice through connexin 43

Figure 1 Glial cell line-derived neurotrophic factor alleviates colitis symptoms in dextran sodium sulfate-induced ulcerative colitis mice. A: Monitoring of body weight changes from day 1 to day 10; B: Daily calculation of the disease activity index scores from day 1 to day 10; C: Measurement of colon length on day 11 after euthanasia. Data were expressed as mean ± SD (n = 8). ^aP < 0.05. ^bP < 0.01. GDNF: Glial cell line-derived neurotrophic factor; UC: Ulcerative colitis; CN: Normal control.