Modified Pulsatilla decoction alleviates 5-fluorouracil-induced intestinal mucositis by modulating the TLR4/MyD88/NF-κB pathway and gut microbiota

Figure 8 Modified Pulsatilla decoction enhances intestinal barrier function. A-F: Expression levels and average fluorescence intensity of Occludin-1 (A and B), Claudin-1 (C and D), ZO-1 (E and F); G and H: Immunohistochemical staining and scoring of Mucin-2. Data are presented as mean ± SD (n = 3). ^aP < 0.01 vs control group; ^bP < 0.01 vs 5-fluorouracil group. 5-FU: 5-fluorouracil; LO: Loperamide; PD: Pulsatilla decoction.