Modified Pulsatilla decoction alleviates 5-fluorouracil-induced intestinal mucositis by modulating the TLR4/MyD88/NF-κB pathway and gut microbiota

Figure 4 Modified Pulsatilla decoction alleviates symptoms in intestinal mucositis mice. A: Percentage of initial body weight (%); B: Diarrhea scores; C: Perianal condition; D: Intestinal length; E: H&E staining (60 × and 200 × magnification); F: Length of the small intestine; G: Length of the colon; H: Histopathological scores; I: MPO expression level. Data are shown as mean ± SD (n = 6-8). ^aP < 0.01 vs control group; ^bP < 0.05, ^cP < 0.01 vs 5-fluorouracil group. 5-FU: 5-fluorouracil; LO: Loperamide; PD: Pulsatilla decoction.