Protective effects of autologous bone marrow-derived mesenchymal stem cell transplantation on acute radioactive enteritis in Beagle dogs

Figure 2 Development of a dog model of acute radiation enteritis. A: The dose and volume histogram of the intensity-modulated radiation therapy irradiation plan for 1 dog; B: Kaplan-Meier survival analysis of dogs receiving different treatments. All of the dogs treated without irradiation survived beyond one month (P < 0.05); C: Intestinal damage as observed by endoscopy after different irradiation doses (0, 12, and 26 Gy). Each result is from one out of three independent experiments, respectively; D: Characteristics of intestinal tissue specimens after 0, 12, and 26 Gy irradiation as revealed by hematoxylin & eosin staining (n = 3 dogs/group). Bars, 500 μm.