Protective effects of autologous bone marrow-derived mesenchymal stem cell transplantation on acute radioactive enteritis in Beagle dogs

doi:10.3748/wjg.v31.i7.97599

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Feb 21, 2025 (publication date) through Apr 13, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2025; 31(7): 97599
Published online Feb 21, 2025. doi: 10.3748/wjg.v31.i7.97599

Table 2 Histologic score before and after autologous bone marrow-derived mesenchymal stem cell transplantation

Group	Time	Mucosa damage	Inflammatory infiltration	Vascular congestion	Total score
Blank		0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
Saline	Before transplantation	2.6 ± 0.5	2.6 ± 0.5	1.6 ± 0.5	6.8 ± 1.6
Saline	After transplantation	2.2 ± 0.4	1.8 ± 0.8	1.4 ± 0.5	5.2 ± 1.6
ABMSCs	Before transplantation	2.4 ± 0.5	2.8 ± 0.4	1.4 ± 0.5	6.6 ± 1.3
ABMSCs	After transplantation	1.6 ± 0.5	1.2 ± 0.4^a	1.0 ± 0.0	3.8 ± 0.8^a

^aP < 0.05, vs before autologous bone marrow-derived mesenchymal stem cell transplantation.

Relative scores of mucosa damage, inflammatory infiltration, and vascular congestion were set from 0 (absent) to 4 (maxim of each aspect, ++++) and the total score of each group was calculated. Histologic scores of different groups were recorded as the mean ± SD. ABMSCs: Autologous bone marrow-derived mesenchymal stem cells.

Citation: Sun GC, Xu WD, Yao H, Chen J, Chai RN. Protective effects of autologous bone marrow-derived mesenchymal stem cell transplantation on acute radioactive enteritis in Beagle dogs. World J Gastroenterol 2025; 31(7): 97599
URL: https://www.wjgnet.com/1007-9327/full/v31/i7/97599.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i7.97599