Mesalazine alleviated the symptoms of spontaneous colitis in interleukin-10 knockout mice by regulating the STAT3/NF-κB signaling pathway

Figure 1 Effect of mesalazine on alleviating symptoms of spontaneous colitis in interleukin-10^-/- mice. A: Daily mouse body weight; B: Disease activity index score; C: Colon length and statistical chart; D: Histological image of the colon of the mouse (hematoxylin & eosin, magnification × 100). The wild group and interleukin-10^-/- group were given normal saline every day and the mice in the 5-amino salicylic acid group were given mesalazine every day. n = 6-8. Compared with the interleukin-10^-/- group, ^aP < 0.05. WT: Wild type; IL: Interleukin; ASA: Amino salicylic acid; NS: No significance.