Internal transcribed spacer sequencing to explore the intrinsic composition of fungal communities in fungal esophagitis

Figure 4 Specific species differences in the three groups. A: Venn diagram based on amplicon sequence variant (ASV) level. Each color block represents a group, and the overlapping areas between the color blocks indicate the ASVs shared among the corresponding groups. The number of each block indicates the number of ASVs contained in that block; B: Linear discriminant analysis Effect Size (LEfSe) analysis of the esophageal normal controls (NCs) group and fungal esophagitis (FE) group at genus level; C: Random forest analysis of NCs group and FE group at genus level; D: LEfSe analysis of suspected FE group and FE group at genus level; E: Random forest analysis of suspected FE group and FE group at genus level; F: LEfSe analysis of suspected FE group and NCs group at genus level; G: Random forest analysis of suspected FE group and NCs group at genus level; H: Receiver operating characteristic (ROC) curve of Candida species relative abundance in the NCs group and FE group; I: ROC curve of Candida species relative abundance in the NCs group and suspected FE group. NC: The esophageal normal control; NFE: Suspected fungal esophagitis; FE: Fungal esophagitis.