Differences in diversity and composition of mucosa-associated colonic microbiota in colorectal cancer and non-colorectal cancer in Indonesia

Table 5 Comparison of gut microbiota composition based on species rank

Microbiota	Colorectal cancer, median (minimum-maximum) (n = 35)	Non-colorectal cancer, median (minimum-maximum) (n = 24)	P value	Adjusted P value
Citrobacter koseri	2.49 (0-26.9)	3.67 (0-26.7)	0.51	0.83
Faecalibacterium prausnitzii	0.20 (0-8.90)	3.92 (0-17.5)	0.001b	< 0.001b
Prevotella copri	0.02 (0-17.5)	1.10 (0-19.6)	0.04a	0.003a
Bacteroides fragilis	0.68 (0-15.2)	0.03 (0-7.89)	0.002a	0.01a
Haemophilus parainfluenzae	0 (0-5.38)	0.37 (0-11.5)	0.004a	0.47
Fusobacterium nucleatum	0.07 (0-44.6)	0 (0-0.16)	0.003a	< 0.001b
Prevotella hominis	0 (0-1.06)	0.04 (0-1.31)	0.05	0.14
Parvimonas micra	0.01 (0-6.94)	0 (0-0.27)	0.001a	0.07
Peptostreptococcus stomatis	0.01 (0-9.81)	0 (0-0.20)	< 0.001b	0.68
Enterococcus faecalis	0 (0-12.3)	0 (0-0.67)	0.004a	< 0.001b
Campylobacter hominis	0 (0-5.45)	0 (0-0.06)	0.008a	0.002a

^aP < 0.05.

^bP < 0.001.

Adjusted P value: P value after adjustment for age and gender. The adjusted P value was calculated using a generalized linear model with gamma distribution and log link.