Differences in diversity and composition of mucosa-associated colonic microbiota in colorectal cancer and non-colorectal cancer in Indonesia

Table 4 Comparison of gut microbiota composition based on genus rank

Microbiota	Colorectal cancer, median (minimum-maximum) (n = 35)	Non-colorectal cancer, median (minimum-maximum) (n = 24)	P value	Adjusted P value
Fusobacterium	4.12 (0-55.0)	0.06 (0-82.6)	0.17	0.67
Faecalibacterium	1.15 (0-13.3)	17.6 (0-41.8)	< 0.001b	< 0.001b
Citrobacter	2.13 (0-23.5)	3.32 (0-24.1)	0.43	0.73
Prevotella	1.48 (0-30.7)	1.34 (0-21.2)	0.56	0.17
Bacteroides	2.11 (0-16.3)	0.37 (0-7.70)	0.02a	0.03a
Clostridium	0.63 (0-10.2)	0.60 (0.02-36.3)	0.90	0.48
Kluyvera	0.82 (0-10.2)	1.48 (0-11.7)	0.45	0.62
Vescimonas	0.48 (0-20.6)	0.36 (0-5.34)	0.13	0.21
Franconibacter	0.69 (0-10.6)	0.94 (0-6.22)	0.61	0.85
Phocaeicola	0.18 (0-6.27)	1.28 (0-12.4)	0.03a	< 0.001b
Campylobacter	0.06 (0-23.5)	0 (0-0.05)	< 0.001b	< 0.001b
Klebsiella	0.51 (0-5.90)	0.41 (0-2.18)	0.76	0.16
Haemophilus	0.01 (0-5.02)	0.34 (0-12.8)	0.003a	< 0.001b
Peptostreptococcus	0.07 (0-9.41)	0 (0-0.20)	< 0.001b	< 0.001b
Parvimonas	0.06 (0-6.13)	0 (0-0.24)	< 0.001b	0.005a

^aP < 0.05.

^bP < 0.001.

Adjusted P value: P value after adjustment for age and gender. The adjusted P value was calculated using a generalized linear model with gamma distribution and log link.