Differences in diversity and composition of mucosa-associated colonic microbiota in colorectal cancer and non-colorectal cancer in Indonesia

Table 3 Comparison of gut microbiota composition based on family rank

Microbiota	Colorectal cancer, median (minimum-maximum) (n = 35)	Non-colorectal cancer, median (minimum-maximum) (n = 24)	P value	Adjusted P value
Enterobacteriaceae	6.53 (0-65.65)	8.83 (0-63.87)	0.55	0.94
Lachnospiraceae	11.38 (0.32-61.55)	9.57 (0.02-44.69)	0.62	0.43
Oscillospiraceae	4.72 (0.0149.15)	21.29 (0.01-44.40)	0.01a	0.009a
Fusobacteriaceae	4.03 (0-54.94)	0.06 (0-82.59)	0.18	0.69
Prevotellaceae	1.94 (0-31.06)	1.31 (0-28.43)	0.65	0.16
Bacteroidaceae	2.70 (0.01-16.19)	2.46 (0-15.27)	0.68	0.30
Veillonellaceae	1.29 (0-27.40)	0.56 (0-12.40)	0.56	0.06
Clostridiaceae	1.20 (0.02-10.15)	0.65 (0.02-36.03)	0.02a	0.11

^aP < 0.05.

Adjusted P value: P value after adjustment for age and gender. The adjusted P value was calculated using a generalized linear model with gamma distribution and log link.