Prognostic roles nutritional index in patients with resectable and advanced biliary tract cancers

Table 1 Basic information of the original studies included

Ref.	Country	Patient number	Tumor location	Tumor status	PNI on OS				PNI on DFS
					HR	LL	UL	Cut off	HR	LL	UL	Cut off
Huang et al[32], 2024	China	159	iCCA	Resectable	3.236	1.6078	6.5131	Median
Utsumi et al[33], 2024	Japan	146	BTC	Resectable	2.17	1.21	3.82	42	2.14	1.09	4.18
Utsumi et al[34], 2024	Japan	148	BTC	Resectable	5.07	1.55	18.87	42
Zhu et al[35], 2023	China	571	iCCA	Resectable	1.585	1.1164	2.2503	48				48
Matsumoto et al[36], 2024	Japan	138	dCCA	Resectable	1.78	1.12	2.82	45	1.74	1.06	2.85	45
Yang et al[37], 2023	China	83	BTC	Advanced	4.367	1.815	10.5075	44.3	3.096	1.4064	6.8154	44.3
Li et al[38], 2023	China	151	iCCA	Resectable (84%)	1.307	0.361	4.726	37.71
Hayashi et al[39], 2023	Japan	89	hCCA	Resectable	1.02	0.53	1.95	45
Cao et al[40], 2022	China	198	GBC	Resectable	3.876	2.525	5.952	45.88
Wang et al[41], 2021	China	639	CCA	Resectable	1.182	0.843	1.657	45
Wang et al[41], 2021	China	639	GBC	Resectable	1.893	1.278	2.805	45
Jin et al[42], 2021	China	328	CCA	Resectable	1.587	0.989	2.5466	44
Utsumi et al[43], 2021	Japan	117	BTC	Resectable	2.12	1.09	4.04	42	1.29	0.58	3.08	42
Salati et al[44], 2020	Italy	114	BTC	Advanced	3.045	1.5602	5.943	36.7
Akgül et al[45], 2018	United States	637	iCCA	Resectable	1.71	1.15	2.53	40
Zhan g et al[46], 2016	China	173	iCCA	Advanced	1.548	1.0965	2.1853	47.1
Deng et al[47], 2016	China	315	GBC	Resectable	1.63	1.193	2.232	46.14

PNI: Prognostic nutritional index; OS: Overall survival; DFS: Disease-free survival; HR: Hazard ratio; CCA: Cholangiocarcinoma; BTC: Biliary tract cancer; GBC: Gallbladder cancer; LL: Lower limit; UL: Upper limit; iCCA: Intrahepatic cholangiocarcinoma; dCCA: Distal cholangiocarcinoma; hCCA: Hilar cholangiocarcinoma.