Keratin 1 modulates intestinal barrier and immune response via kallikrein kinin system in ulcerative colitis

Figure 4 Anti-inflammatory effects of keratin 1 protein in mice with dextran sulfate sodium-induced colitis. A-C: Relative body weight changes; D: Representative images of colons; E: Colon length measurements for each group; F: Disease activity index score; G: Enzyme-linked immunosorbent assay (ELISA) quantitative of bradykinin; H: ELISA quantitative of interleukin-1β; I: ELISA quantitative of interleukin-6; J: ELISA quantitative of tumor necrosis factor-α. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. P value vs control group. DSS: Dextran sulfate sodium; DAI: Disease activity index; ELISA: Enzyme-linked immunosorbent assay; BK: Bradykinin; IL: Interleukin; TNF: Tumor necrosis factor.