Histopathological diagnosis of microvascular invasion in hepatocellular carcinoma: Is it reliable?

Figure 5 Quantity and distribution of microvascular invasion detected by different sampling protocols. A: Box plot showing the number of microvascular invasion (MVI) lesions detected by various sampling protocols. The Wilcoxon matched-pairs signed-rank sum test was employed to compare protocol A vs B, B vs C, and C vs D, whereas the Mann-Whitney U test was used to compare protocol D vs E; B: Trend of in the number of MVI lesion detected in different metastatic distance groups for each sampling protocol; C: Percentage distribution of the number of MVI lesions detected in different metastatic distance groups for each sampling protocol. MVI: Microvascular invasion; WSI: Whole-mount slide imaging.