Histopathological diagnosis of microvascular invasion in hepatocellular carcinoma: Is it reliable?

Figure 2 Schematic illustration of various sampling protocols based on whole-mount slide images. A: Protocol A, six regions (labeled a-f) in the maximal tumor section; B: Protocol B, a single complete whole-mount slide image of the maximal tumor section (number 4); C: Protocol C, whole-mount slide images that included the tumor sections at 3 mm intervals (numbers 3-5); D: Protocol D, whole-mount slide images that included the entire liver at 3 mm intervals (numbers 1-7); E: Protocol E, whole-mount slide images that included the entire liver at 0.3 mm intervals.