Imaging characteristics of brain microstructure and cerebral perfusion in Crohn’s disease patients with anxiety: A prospective comparative study

Figure 1 Intravoxel incoherent motion diffusion-weighted images from a 37-year-old man with Crohn’s disease and a 35-year-old healthy control man. A: Slow apparent diffusion coefficient (ADC_slow) map from biexponential fitting with 10 b-values. The left frontal ADC_slow values were 0.000779326 in the healthy control (HC) group and 0.000832584 in the Crohn’s disease (CD) patients measured by SPM12. The color scale from blue to red represents the range of ADC_slow values (0.000100-0.00250 × 10^-3 mm²/second); B: Fast apparent diffusion coefficient (ADC_fast) map from biexponential fitting with 10 b-values. The left frontal ADC_fast values were 0.016722 in the HC group and 0.019411 in the CD patients measured by SPM12. The color scale from blue to red represents the range of ADC_fast values (0.0100-0.0300 × 10^-2 mm²/seconds); C: Perfusion fraction (f) map from biexponential fitting with 10 b-values. The left frontal ADC_fast values were 0.117279 in the HC group and 0.115245 in the CD patients measured by SPM12. The color scale from blue to red represents the range of f values (-0.180% to 0.266%). HC: Healthy control; CD: Crohn’s disease.