Imaging characteristics of brain microstructure and cerebral perfusion in Crohn’s disease patients with anxiety: A prospective comparative study

Table 4 Perfusion fraction values in the participants

Brain ROI	f value			P value1
	CD with anxiety (n = 16)	CD without anxiety (n = 21)	Healthy controls (n = 20)
Left frontal lobe	0.136 ± 0.026	0.140 ± 0.023	0.140 ± 0.017	0.116
Left parietal lobe	0.120 ± 0.021	0.113 ± 0.018	0.124 ± 0.021	0.614
Left temporal lobe	0.113 ± 0.021	0.104 ± 0.013	0.097 ± 0.011	0.190
Left occipital lobe	0.111 ± 0.038	0.101 ± 0.026	0.097 ± 0.021	0.517
Left insular lobe	0.110 ± 0.021	0.106 ± 0.027	0.092 ± 0.017	0.160
Right frontal lobe	0.142 ± 0.033	0.131 ± 0.014	0.122 ± 0.015	0.148
Right parietal lobe	0.113 ± 0.033	0.106 ± 0.019	0.101 ± 0.020	0.548
Right temporal lobe	0.099 ± 0.024	0.101 ± 0.012	0.096 ± 0.034	0.782
Right occipital lobe	0.102 ± 0.036	0.094 ± 0.018	0.094 ± 0.024	0.719
Right insular lobe	0.109 ± 0.037	0.111 ± 0.028	0.088 ± 0.024	0.267

¹One-way analysis of variance.

f: Perfusion fraction; ROI: Region of interest; CD: Crohn’s disease.