Imaging characteristics of brain microstructure and cerebral perfusion in Crohn’s disease patients with anxiety: A prospective comparative study

Table 3 Fast apparent diffusion coefficient values in the participants

Brain ROI	ADCfast Value (10-2 mm2/second)			P value1
	CD with anxiety (n = 16)	CD without anxiety (n = 21)	Healthy controls (n = 20)
Left frontal lobe	0.183 ± 0.017	0.171 ± 0.083	0.150 ± 0.025	< 0.001a
Left parietal lobe	0.189 ± 0.031	0.181 ± 0.027	0.216 ± 0.010	0.372
Left temporal lobe	0.186 ± 0.035	0.176 ± 0.085	0.153 ± 0.013	< 0.001a
Left occipital lobe	0.159 ± 0.019	0.169 ± 0.017	0.186 ± 0.033	0.437
Left insular lobe	0.198 ± 0.013	0.181 ± 0.011	0.153 ± 0.024	< 0.001a
Right frontal lobe	0.183 ± 0.017	0.181 ± 0.019	0.164 ± 0.011	0.001a
Right parietal lobe	0.184 ± 0.036	0.193 ± 0.024	0.254 ± 0.017	0.142
Right temporal lobe	0.197 ± 0.033	0.182 ± 0.015	0.164 ± 0.019	< 0.001a
Right occipital lobe	0.159 ± 0.019	0.169 ± 0.017	0.163 ± 0.019	0.437
Right insular lobe	0.122 ± 0.014	0.154 ± 0.019	0.178 ± 0.027	< 0.001a

¹One-way analysis of variance.

^aP < 0.05.

ADC_fast: Fast apparent diffusion coefficient; ROI: Region of interest; CD: Crohn’s disease.