C-X-C chemokine receptor type 5+CD8+ T cells as immune regulators in hepatitis Be antigen-positive chronic hepatitis B under interferon-alpha treatment

Figure 5 Comparison of C-X-C chemokine receptor type 5 and programmed death-ligand 1 expression on peripheral blood mononuclear cells and CD8⁺ lymphocytes between the serologic response and non-serologic response groups at different time points. A: C-X-C chemokine receptor type 5 (CXCR5) expression on peripheral blood mononuclear cells (PBMCs); B: Programmed death-ligand 1 (PD-L1) expression on PBMCs; C: CXCR5 expression on CD8+ lymphocytes; D: PD-L1 expression on CD8⁺ lymphocytes. SR: Serologic response; NSR: Non-serologic response; CXCR5: C-X-C chemokine receptor type 5; PD-L1: Programmed death-ligand 1.