C-X-C chemokine receptor type 5+CD8+ T cells as immune regulators in hepatitis Be antigen-positive chronic hepatitis B under interferon-alpha treatment

doi:10.3748/wjg.v31.i3.99833

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2025; 31(3): 99833
Published online Jan 21, 2025. doi: 10.3748/wjg.v31.i3.99833

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Figure 4 Dynamic changes of various markers over time. A: Hepatitis B virus DNA levels; B: HBsAg levels; C: Hepatitis Be antigen; D: Frequency of C-X-C chemokine receptor type 5⁺CD8⁺ cells; E: Interleukin-21 concentration; F: Programmed death-ligand 1 expression. SR: Serologic response; NSR: Non-serologic response; HBeAg: Hepatitis Be antigen; IL-21: Interleukin-21; CXCR5: C-X-C chemokine receptor type 5; PD-L1: Programmed death-ligand 1.

Citation: Xu ZY, Dai ZS, Gong GZ, Zhang M. C-X-C chemokine receptor type 5⁺CD8⁺ T cells as immune regulators in hepatitis Be antigen-positive chronic hepatitis B under interferon-alpha treatment. World J Gastroenterol 2025; 31(3): 99833
URL: https://www.wjgnet.com/1007-9327/full/v31/i3/99833.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i3.99833