C-X-C chemokine receptor type 5+CD8+ T cells as immune regulators in hepatitis Be antigen-positive chronic hepatitis B under interferon-alpha treatment

Figure 2 Frequency of CD8⁺ and CD4⁺ T cells expressing C-X-C chemokine receptor type 5 and programmed death-ligand 1 in a single chronic hepatitis B patient at baseline. A: Frequency of C-X-C chemokine receptor type 5 (CXCR5)⁺CD8⁺ T cells; B: Frequency of CXCR5⁺CD4⁺ T cells; C: Frequency of programmed death-ligand 1 (PD-L1) ⁺CD8⁺ T cells; D: Frequency of PD-L1⁺CD4⁺ T cells. CXCR5: C-X-C chemokine receptor type 5; PD-L1: Programmed death-ligand 1.