In silico analysis of lncRNA-miRNA-mRNA signatures related to Sorafenib effectiveness in liver cancer cells

Figure 7 Identification of protein interactions at 24 hours. A and B: Identification of protein interactions at 24 hours. STRING pathways of targets regulated by lncRNAs or miRNAs with no more than 10 interactions in HepG2 and SNU499 cells treated with Sorafenib (24 hours); C and D: Top 3 enriched Gene Ontology and Kyoto Encyclopedia of Genes and Genome terms in the STRING pathway analysis in HepG2 and SNU499 cells treated with Sorafenib (24 hours); E-G: Validation of proposed interaction networks using GEPIA data between MALAT1 and TFAP4, and MALAT and SMAD7 in HepG2 cells, and PVT1 and VEGFA in SNU449 cells.