Predicting colorectal adenomatous polyps in patients with chronic liver disease: A novel nomogram

Table 2 Baseline characteristics of adenomatous polyp cohort in training and validation group

Variables	Total (n = 596)	Training group (n = 432)	Validation group (n = 164)	χ2/t/Z	P value
Male, n (%)	324 (54.4)	90 (54.9)	234 (54.2)	0.024	0.876
Age (year), mean ± SD	53.02 ± 11.14	53.04 ± 11.24	52.96 ± 10.91	0.089	0.929
BMI (kg/m²), mean ± SD	25.66 ± 3.94	25.78 ± 3.94	25.31 ± 3.93	1.323	0.186
Alcohol, n (%)	179 (30.0)	127 (29.4)	52 (31.7)	0.302	0.583
Smoking, n (%)	193 (32.4)	145 (33.6)	48 (29.3)	1.002	0.317
Diabetes, n (%)	154 (25.8)	120 (27.8)	34 (20.7)	3.080	0.079
Hypertension, n (%)	165 (27.7)	120 (27.8)	45 (27.4)	0.007	0.934
MS, n (%)	96 (16.1)	69 (16.0)	27 (16.5)	0.021	0.884
Cirrhosis, n (%)	285 (47.8)	215 (49.8)	70 (42.7)	2.392	0.122
FPG (mmo/L), mean ± SD	6.15 ± 2.07	6.23 ± 2.16	5.93 ± 1.85	-1.573	0.116
HDL (mmo/L), mean ± SD	1.33 ± 0.40	1.33 ± 0.41	1.33 ± 0.38	0.105	0.916
CHO (mmo/L), median (IQR)	4.54 (3.82, 5.38)	4.57 (3.81, 5.40)	4.41 (3.85, 5.41)	-0.714	0.458
TG (mmo/L), mean ± SD	1.42 ± 1.12	1.44 ± 1.22	1.35 ± 0.82	-0.826	0.409
LDL (mmo/L), mean ± SD	2.81 ± 0.90	2.75 ± 0.82	2.83 ± 0.93	-0.979	0.382
TP (g/L), mean ± SD	71.54 ± 7.98	71.29 ± 7.76	72.19 ± 8.51	1.239	0.216
ALB (g/L), mean ± SD	40.75 ± 6.14	40.83 ± 6.07	40.52 ± 6.34	-0.551	0.582
SI (μmol/L), mean ± SD	22.36 ± 10.67	22.37 ± 10.15	22.33 ± 11.97	-0.040	0.968
SF (ug/L), median (IQR)	165.00 (70.25, 303.25)	163.00 (76.00, 304.00)	174.00 (54.50, 295.00)	-0.721	0.471
TRF (g/L), mean ± SD	2.75 ± 0.89	2.75 ± 0.91	2.76 ± 0.83	0.203	0.840
TSH (mIU/L), median (IQR)	1.85 (1.33, 2.83)	1.94 (1.30, 2.89)	1.72 (1.34, 2.66)	-1.435	0.151
FT4 (pmol/L), mean ± SD	17.10 ± 14.18	17.31 ± 9.77	16.57 ± 9.62	-0.698	0.485
FT3 (pmol/L), mean ± SD	4.98 ± 1.00	5.01 ± 1.02	4.90 ± 0.94	-1.245	0.214
ALT (IU/L), median (IQR)	33.20 (19.40, 78.57)	32.20 (19.10, 76.57)	34.75 (19.65, 79.25)	-0.610	0.542
AST (IU/L), median (IQR)	33.75 (22.35, 72.47)	33.75 (22.02, 65.60)	34.10 (22.62, 78.75)	-0.491	0.624
GGT (IU/L), median (IQR)	53.85 (24.35, 116.77)	54.55 (24.97, 100.57)	50.05 (22.07, 163.45)	-0.274	0.708

BMI: Body mass index; MS: Metabolic syndrome; FPG: Fasting plasma glucose; HDL: High-density lipoprotein; CHO: Cholesterol; TG: Triacylglycerol; LDL: Low-density lipoprotein; PLT: Platelet count; TP: Total protein; ALB: Albumin; SI: Serum iron; SF: Serum ferritin; TRF: Transferrin; TSH: Thyroid-stimulating hormone; FT3: Free T3; FT4: Free T4; ALT: Alanine aminotransferase; AST: Aspartate transaminase; GGT: Gamma-glutamyl transferase; IQR: Interquartile range.