Bicuculline ameliorates metabolic dysfunction-associated steatotic liver disease by inhibiting the nuclear factor-kappa B pathway and reducing lipid accumulation

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May 7, 2025 (publication date) through Apr 29, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. May 7, 2025; 31(17): 105438
Published online May 7, 2025. doi: 10.3748/wjg.v31.i17.105438

Table 2 Primer sequences of mouse for RT-qPCR

Primer	Primer sequence (5’-3’)	Primer sequence (5’-3’)
GAPDH	CGACTTCAACAGCAACTCCCACTCTTCC	TGGGTGGTCCAGGGTTTCTTACTCCTT
Srebf1	AGCCATCGACTACATCCG	TCCATAGACACATCTGTGCCTC
Fasn	TGGTGGTGTGGACATGGTCACAGA	CCGAAGCTGGGGGTCCATTGTGTG
Scd1	ACACCATGGCGTTCCAGAAT	AGCTTCTCGGCTTTCAGGTC
Dgat1	TCGTGGTATCCTGAATTGGTG	AGGTTCTCTAAAAATAACCTTGCATT
Dgat2	GCTGGTGCCCTACTCCAAG	CCAGCTTGGGGACAGTGA
IL-1β	GAAATGCCACCTTTTGACAGTG	TGGATGCTCTCATCAGGACAG
COX-2	TTCCAATCCATGTCAAAACCGT	AGTCCGGGTACAGTCACACTT
TNF-α	AGGAGGAATTTGGCCAGGTG	GCTCACGAGGAGGCTAATCC

Citation: Wang XM, Dai Z, Lu DJ, Bao CQ, Yang NB, Zhou YP. Bicuculline ameliorates metabolic dysfunction-associated steatotic liver disease by inhibiting the nuclear factor-kappa B pathway and reducing lipid accumulation. World J Gastroenterol 2025; 31(17): 105438
URL: https://www.wjgnet.com/1007-9327/full/v31/i17/105438.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i17.105438