Machine learning algorithms reveal gut microbiota signatures associated with chronic hepatitis B-related hepatic fibrosis

Figure 3 Identification of differential gut microbiota features in patients in mild hepatic fibrosis and significant hepatic fibrosis groups and different stages of hepatic fibrosis. A-C: The relative abundance at the phylum level: Firmicutes (A); Verrucomicrobia (B); Acidobacteria (C); D: The relative abundance of Parabacteroides at the genus level; E: The Parabacteroides/Bacteroidetes ratio in mild hepatic fibrosis and significant hepatic fibrosis groups; F-H: The relative abundance at the phylum level: Spirochaetes (F); Ruminococcaceae Ruminococcus (G); Dorea (H); I: The Dorea/Firmicutes ratio in different stages of hepatic fibrosis. All data were analyzed by the Mann-Whitney U test. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. mHF: Mild hepatic fibrosis; sHF: Significant hepatic fibrosis.