Interventional effect of hesperetin on N-methyl-N’-nitro-N-nitrosoguanidine-induced exosomal circ008274 in affecting normal cells to promote gastric carcinogenesis

Figure 2 Intervention effect of hesperetin on TGES-1 cells. A: Cell Counting Kit-8 (CCK-8) detection of the survival rate of TGES-1 cells; B: CCK-8 detection of the proliferation ability of TGES-1 cells; C: Alteration of the clonogenic ability of TGES-1 cells; D: Alteration of the migratory and invasive abilities of TGES-1 cells; E: Protein levels of epithelial-to-mesenchymal transition (EMT), stemness, and proliferative markers; F: mRNA levels of EMT, stemness, and proliferative markers. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. ^dP < 0.0001. DMSO: Dimethyl sulfoxide; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; MNNG: N-methyl-N’-nitro-N-nitrosoguanidine; OD: Optical density.