Epstein-Barr virus infection is an independent risk factor for surgery in patients with moderate-to-severe ulcerative colitis

Table 4 Results of multivariate logistic analysis

	Multivariate logistic analysis
	P value	OR (95%CI)
Age (year)	0.004a	1.063 (1.020, 1.107)
Fever	0.288	2.038 (0.549, 7.568)
EBER positivity	0.003a	9.634 (2.137, 43.424)
CMV positivity	0.001a	118.825 (6.839, 2064.630)
C-reactive protein (mg/L)	0.116	1.013 (0.997, 1.029)
ESR (mm/hour)	0.429	1.010 (0.985, 1.037)
Treatment with ≥ 3 types of immunosuppressive drugs before admission	0.000a	17.959 (4.638, 69.540)
Antibiotic therapy with third-generation cephalosporins or more advanced antibiotics during admission	0.130	2.948 (0.728, 11.934)

^aP < 0.05.

EBER: Epstein-Barr virus-encoded small RNA; CMV: Cytomegalovirus; ESR: Erythrocyte sedimentation rate; OR: Odds ratio.