LncRNA FTX promotes colorectal cancer radioresistance through disturbing redox balance and inhibiting ferroptosis via miR-625-5p/SCL7A11 axis

Figure 7 Inhibition of lncRNA FTX increases the radiosensitivity of colorectal cancer in vivo. A: Representative images of the tumors after receiving or not by 10 Gy irradiation, formed by HT29R-sh-FTX or control cells subcutaneous vaccination; B: Tumor volume in xenograft mice of each group at the indicated times; C: Tumor weights of xenograft mice from each group; D: Representative immunohistochemical staining images of Ki-67, SLC7A11, and 4-HNE in the subcutaneous tumor xenograft tissues. Scale bar: 50 μm. Data are expressed mean ± SD. ^aP < 0.05 and ^bP < 0.01. NC: Negative control; IR: Ionizing radiation.