Predictive models and clinical manifestations of intrapulmonary vascular dilatation and hepatopulmonary syndrome in patients with cirrhosis: Prospective comparative study

Figure 6 Predictive model for hepatopulmonary syndrome combining clinical parameters and biomarkers. A: Nomogram of the predictive model for hepatopulmonary syndrome (HPS) in patients with cirrhosis. This model integrates two clinical parameters and six biomarkers; B: Receiver operating characteristic (ROC) curve predicting HPS in patients with cirrhosis. Area under the curve (AUC) was 0.891 (95% confidence interval [CI]: 0.848-0.934); C: Calibration curves; D: Decision curve analysis of the nomogram for the prediction of HPS. ALB: Albumin; HGB: Hemoglobin; FPR: False-positive rate; P(A-a)O₂: Alveolar-arterial oxygen gradient; PDGF-BB: Platelet-derived growth factor BB; S1P: Sphingosine 1 phosphate; TBIL: Total bilirubin; TPR: True-positive rate.