Predictive models and clinical manifestations of intrapulmonary vascular dilatation and hepatopulmonary syndrome in patients with cirrhosis: Prospective comparative study

Figure 5 Predictive model for intrapulmonary vascular dilatation combining clinical parameters and biomarkers. A: Nomogram of the predictive model for intrapulmonary vascular dilatation (IPVD) in patients with cirrhosis. This model integrates four clinical parameters and three biomarkers; B: Receiver operating characteristic (ROC) curve predicting IPVD in patients with cirrhosis. Area under the curve (AUC) was 0.792 (95% confidence interval [CI]: 0.737-0.847); C: Calibration curves; D: Decision curve analysis of the nomogram for the prediction of IPVD. FPR: False-positive rate; MELD: Model for End-Stage Liver Disease; P(A-a)O₂: Alveolar-arterial oxygen gradient; PDGF-BB: Platelet-derived growth factor BB; S1P: Sphingosine 1 phosphate; TPR: True-positive rate.