Multi-omics reveals the associations among the fecal metabolome, intestinal bacteria, and serum indicators in patients with hepatocellular carcinoma

Table 2 Receiver operating characteristic analysis of serum indicators

Characteristic	HC vs HCC12		HC vs HCC34
	AUC	P value	AUC	P value
BMI	0.7047	0.0335	0.7000	0.0328
ALT	0.6550	0.1074	0.5684	0.4651
AST	0.8816	< 0.0001	0.9842	< 0.0001
ALB	0.9737	< 0.0001	1	< 0.0001
ALP	0.6170	0.2242	0.8132	0.0008
GGT	0.9064	< 0.0001	0.9289	< 0.0001
TBIL	0.8553	0.0002	0.9263	< 0.0001
AFP	0.9474	< 0.0001	0.9763	< 0.0001

HC: Healthy control; HCC12: Comprising patients with stage I and II hepatocellular carcinoma; HCC34: Comprising patients with stage III and IV hepatocellular carcinoma; BMI: Body mass index; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALB: Albumin; ALP: Alkaline phosphatase; GGT: γ-glutamyl transferase; TBIL: Total bilirubin; AFP: Alpha-fetoprotein.