Strain- and sex-dependent variability in hepatic microcirculation and liver function in mice

Figure 1 Comparative analysis of hepatic microcirculatory blood perfusion and characteristic oscillatory amplitudes between sexes and across three mouse strains. A: Hepatic microcirculatory blood perfusion patterns in the BALB/c, C57BL/6J, and KM mouse strains. The rectangular insert highlights the extracted pattern of microcirculatory blood distribution; B and C: Two-dimensional and three-dimensional spectral scalograms representing the characteristic amplitudes of hepatic microcirculation profiles; D: Quantitative analysis of characteristic oscillatory amplitudes in hepatic microcirculatory blood perfusion profiles. The data are presented as the mean ± SEM. n = 6 each group. ^aP < 0.05. ^cP < 0.001. AU: Amplitude; NO: Nitric oxide; NS: Not significant; PU: Perfusion unit.