Extramural venous invasion in gastric cancer: 9.4T magnetic resonance imaging assessment and circular RNA functional analysis

Figure 4 Extramural venous invasion in gastric cancer orthotopic mouse model perpendicular to the plane of magnetic resonance imaging axial image. A: T2-weighted fat-suppressed images, gastric cancer is manifested as a significant thickening of the gastric wall with heterogeneous signal intensity (within the red circle); B: Extramural venous invasion-detected detected on magnetic resonance imaging (mrEMVI) is visible as a tubular structure with a slightly high signal (orange arrow); C: This tubular structure can be observed in continuous layers and is connected to both the tumor and nearby blood vessels (white arrow); D: Hematoxylin and eosin staining of tumor (10 × and 200 ×); E: Alpha-smooth muscle actin staining (200 ×); F: CD34 staining (200 ×). ¹Extramural venous invasion; T: Tumor; red dashed line: Tumor boundary.