Prognostic scoring system using inflammation- and nutrition-related biomarkers to predict prognosis in stage I-III colorectal cancer patients

Table 2 Univariate Cox analyses for overall survival of inflammation-related and nutrition-related biomarkers in the training set

Variable	Cutoff value	Categories	HR	95%CI	P value
NLR	2.07	High (≥ 2.07) vs low (< 2.07)	3.07	1.86, 5.05	< 0.001
MLR	0.28	High (≥ 0.28) vs low (< 0.28)	4.09	2.52, 6.62	< 0.001
PLR	166.66	High (≥ 166.66) vs low (< 166.66)	2.74	1.74, 4.34	< 0.001
PIV	348.45	High (≥ 348.45) vs low (< 348.45)	7.23	4.52, 11.57	< 0.001
SII	576.92	High (≥ 576.92) vs low (< 576.92)	3.40	2.12, 5.44	< 0.001
SIRI	14.15	High (≥ 14.15) vs low (< 14.15)	6.45	4.02, 10.34	< 0.001
PNI	47.05	High (≥ 47.05) vs low (< 47.05)	0.50	0.32, 0.79	0.003
GNRI	103.95	High (≥ 103.95) vs low (< 103.95)	0.40	0.25, 0.63	< 0.001
AGR	1.40	High (≥ 1.40) vs low (< 1.40)	0.23	0.14, 0.38	< 0.001
ALI	367.75	High (≥ 367.75) vs low (< 367.75)	0.27	0.17, 0.42	< 0.001

NLR: Neutrophil to lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio; PLR: Platelet to lymphocyte ratio; ALI: Advanced lung cancer inflammation index; PIV: Pan-immune-inflammation; SII: Systemic immune inflammation index; SIRI: Systemic Inflammation Response Index; PNI: Prognostic nutritional index; GNRI: Geriatric nutrition risk index; AGR: Albumin to globulin ratio; HR: Hazard ratio.