Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study

doi:10.3748/wjg.v31.i14.104584

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Apr 14, 2025 (publication date) through Apr 15, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2025; 31(14): 104584
Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104584

Table 2 Comparison of iron metabolism levels between the two groups of patients

Variables	Total (n = 139)	Sepsis (n = 86)	SALI (n = 53)	P value
SI, μmol/L	7.09 (4.08, 12.59)	4.88 (3.50, 8.04)	12.24 (7.83, 19.37)	< 0.001^a
TIBC, μmol/L	29.16 (23.23, 35.36)	25.69 (20.44, 32.80)	33.02 (29.08, 38.58)	< 0.001^a
sTfR, mg/L	2.21 (1.74, 3.04)	2.17 (1.67, 3.03)	2.22 (1.83, 3.10)	0.328
SF, ng/mL	599.00 (286.00, 1445.00)	456.00 (277.25, 985.75)	866.00 (479.00, 6387.00)	0.001^a
TRF, mg/L	20.96 (17.23, 25.21)	18.79 (16.23, 24.45)	22.39 (18.92, 27.01)	0.005^a
TSAT, %	0.21 (0.15, 0.35)	0.18 (0.13, 0.26)	0.31 (0.17, 0.67)	< 0.001^a

^aP < 0.05.

SALI: Sepsis-associated liver injury; SI: Serum iron; TIBC: Total iron-binding capacity; sTfR: Soluble transferrin receptor; SF: Serum ferritin; TRF: Transferrin; TSAT: Transferrin saturation.

Citation: Wang TW, Zhou LL, Yuan J, Zhou WX, Wang HR, Yu TT, Zhai JC, Tang CB, Jiang W, Yu JQ, Zheng RQ, Yu HL, Shao J. Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study. World J Gastroenterol 2025; 31(14): 104584
URL: https://www.wjgnet.com/1007-9327/full/v31/i14/104584.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i14.104584