Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study

Table 1 Baseline characteristics of the sepsis group and the sepsis-associated liver injury group, n (%)

Variables	Total (n = 139)	Sepsis (n = 86)	SALI (n = 53)	P value
Age, year, mean ± SD	67.74 ± 12.78	68.03 ± 13.51	67.26 ± 11.62	0.731
BMI, kg/m2, mean ± SD	23.36 ± 4.07	23.08 ± 4.24	23.83 ± 3.76	0.292
SOFA score (except liver function), mean ± SD	7.80 ± 3.47	7.42 ± 3.08	8.17 ± 3.81	0.273
APACHE II score, mean ± SD	20.42 ± 7.32	19.81 ± 7.14	21.42 ± 7.58	0.212
ICU stay, days	7.00 (4.00, 13.50)	7.00 (5.00, 16.00)	6.00 (4.00, 10.00)	0.034a
Hospital stay, days	9.00 (5.00, 21.00)	9.50 (6.00, 25.75)	9.00 (2.00, 14.00)	0.037a
Gender				0.265
Male	89 (64.03)	52 (60.47)	37 (69.81)
Female	50 (35.97)	34 (39.53)	16 (30.19)
Smoking history				0.279
No	84 (60.43)	55 (63.95)	29 (54.72)
Yes	55 (39.57)	31 (36.05)	24 (45.28)
Drinking history				< 0.001a
No	94 (67.63)	68 (79.07)	26 (49.06)
Yes	45 (32.37)	18 (20.93)	27 (50.94)
Hypertension				0.921
No	55 (39.86)	34 (39.53)	21 (40.38)
Yes	83 (60.14)	52 (60.47)	31 (59.62)
Diabetes				0.273
No	105 (76.09)	62 (72.94)	43 (81.13)
Yes	33 (23.91)	23 (27.06)	10 (18.87)
Pulmonary infection				0.002a
No	63 (45.32)	30 (34.88)	33 (62.26)
Yes	76 (54.68)	56 (65.12)	20 (37.74)
Abdominal infection				0.002a
No	91 (65.94)	65 (75.58)	26 (50.00)
Yes	47 (34.06)	21 (24.42)	26 (50.00)
Urinary tract infection				0.437
No	125 (89.93)	76 (88.37)	49 (92.45)
Yes	14 (10.07)	10 (11.63)	4 (7.55)
Case fatality, 14 days				0.030a
No	119 (85.61)	78 (90.70)	41 (77.36)
Yes	20 (14.39)	8 (9.30)	12 (22.64)
Case fatality, 28 days				0.277
No	109 (78.42)	70 (81.40)	39 (73.58)
Yes	30 (21.58)	16 (18.60)	14 (26.42)

^aP < 0.05.

SALI: Sepsis-associated liver injury; BMI: Body mass index; SOFA: Sequential Organ Failure Assessment; ICU: Intensive care unit.