Interplay of genetic and clinical factors in cancer-associated thrombosis: Deciphering the prothrombotic landscape of colorectal cancer

Figure 1 Clinical risk factors influencing thrombosis in colorectal cancer. This figure delineates two primary categories of clinical risk factors: General clinical factors and tumor-specific factors. General clinical factors, prevalent in both tumor and non-tumor patients, contribute to the overall risk landscape. However, it is the presence of tumor-specific clinical risk indicators and biological markers unique to malignant tumors that particularly delineates the pathogenesis of thrombosis associated with colorectal cancer. Collectively, these factors precipitate a shift in hemostatic equilibrium, favoring a hypercoagulable state. Created in BioRender (Supplementary material).