Noninvasive prediction of esophagogastric varices in hepatitis B: An extreme gradient boosting model based on ultrasound and serology

Table 1 Basic characteristics, mean ± SD

Index	Total	Train set	Test set	P value
Liver stiffness	13.2 ± 5.0	13.2 ± 5.3	12.9 ± 4.0	0.91
Spv speed	35.3 ± 9.1	35.5 ± 9.3	34.5 ± 8.6	0.4
Platelet count	132.9 ± 63.8	131.3 ± 64.7	139.4 ± 60.2	0.23
Model for end-stage liver disease	30.2 ± 1.9	30.3 ± 1.8	29.9 ± 2.1	0.044
Creatinine	75.5 ± 27.1	76.2 ± 29.6	72.5 ± 12.9	0.74
Alanine aminotransferase	38.0 ± 39.0	36.4 ± 34.6	44.5 ± 52.8	0.046
Aspartate aminotransferase	47.8 ± 62.1	44.7 ± 53.3	60.2 ± 88.4	0.057
Total bilirubin	30.5 ± 34.5	30.7 ± 34.2	29.6 ± 36.0	0.43
Direct bilirubin	16.2 ± 27.8	16.4 ± 27.6	15.5 ± 29.0	0.48
Indirect bilirubin	14.2 ± 9.8	14.3 ± 8.9	14.0 ± 13.0	0.27
Alkaline phosphatase	108.8 ± 55.9	105.2 ± 53.1	123.0 ± 64.4	0.027
Red blood cell count	4.3 ± 0.8	4.3 ± 0.8	4.4 ± 0.7	0.35
White blood cell count	5.3 ± 1.9	5.3 ± 1.9	5.3 ± 1.6	0.64
Age	53.4 ± 12.3	53.6 ± 12.4	52.5 ± 11.8	0.57
Spleen stiffness	15.1 ± 4.8	15.2 ± 4.9	14.8 ± 4.7	0.83
pv	1.2 ± 0.2	1.2 ± 0.2	1.2 ± 0.2	0.59
pvspeed	27.5 ± 6.7	27.2 ± 6.6	28.5 ± 7.2	0.14
splong	13.3 ± 2.6	13.3 ± 2.5	13.4 ± 2.7	0.88
spwide	4.6 ± 1.0	4.7 ± 0.9	4.6 ± 1.0	0.34
spv	0.8 ± 0.2	0.8 ± 0.2	0.9 ± 0.2	0.41
Prothrombin time	15.5 ± 3.2	15.7 ± 3.4	14.8 ± 2.3	0.045
Albumin	39.7 ± 8.9	40.0 ± 8.9	38.6 ± 8.8	0.4
International normalized ratio	1.2 ± 0.3	1.3 ± 0.3	1.2 ± 0.3	0.22
Sex, n (%)
Female	84 (27.1)	67 (27.0)	17 (27.4)	1
Male	226 (72.9)	181 (73.0)	45 (72.6)	-
Child-Pugh class, n (%)
1	168 (54.2)	131 (52.8)	37 (59.7)	0.29
2	119 (38.4)	100 (40.3)	19 (30.6)	-
3	23 (7.4)	17 (6.9)	6 (9.7)	-
Collateral, n (%)
No	244 (78.7)	196 (79.0)	48 (77.4)	0.86
Yes	66 (21.3)	52 (21.0)	14 (22.6)	-
Severe EGV, n (%)
No	186 (60.0)	149 (60.1)	37 (59.7)	1
Yes	124 (40.0)	99 (39.9)	25 (40.3)	-

Spv speed: Spleen vein speed; pv: Portal vein; pvspeed: Portal vein speed; splong: Spleen length; spwide: Spleen width; spv: Splenic vein; EGV: Esophagogastric varices.