Nonalcoholic fatty liver disease following laparoscopic duodenum-preserving pancreatic total head resection vs laparoscopic pancreaticoduodenectomy: A retrospective cohort study

Table 1 Postoperative laboratory and imaging variables of patients with non-alcoholic fatty liver disease or not, n (%)

Variables	Overall (n = 59)	NAFLD group (n = 17)	Not NAFLD group (n = 42)	P value
Surgical procedures				0.022
LPD	35 (59.3)	14 (40.0)	21 (60.0)
LDPPHRt	24 (40.7)	3 (12.5)	21 (87.5)
Until postoperative 1 month
Postoperative bleeding	7 (11.9)	4 (23.5)	3 (7.1)	0.176
DGE	20 (33.9)	5 (29.4)	15 (35.7)	0.643
POPF	13 (22.0)	2 (11.8)	11 (26.2)	0.388
SSI	1 (1.7)	1 (5.9)	0	0.288
Postoperative within 6-12 months
AST (U/L)	23 [17, 32]	27 [21, 37]	23 [17, 32]	0.167
ALT (U/L)	23 [13, 46]	23 [15, 49]	25 [13, 45]	0.657
AST/ALT	1.1 [0.8, 1.5]	1.3 [0.9, 1.5]	1.1 [0.7, 1.4]	0.284
FIB-4 index	1.3 [0.8, 1.9]	1.4 [0.8, 1.9]	1.1 [0.8, 1.9]	0.514
Albumin (g/L)	41.1 [37.2, 45.3]	40.5 [35.2, 43.9]	41.1 [37.5, 45.5]	0.307
Total cholesterol (mmol/L)	3.7 [3.2, 4.3]	3.9 [2.8, 4.5]	3.7 [3.3, 4.1]	0.821
Random blood glucose(mmol/L)	5.6 [5.1, 6.5]	6.0 [5.1, 9.5]	5.6 [5.1, 6.0]	0.312
TBIL (μmol/L)	10.5 [8.0, 15.0]	11.0 [8.3, 14.5]	10.2 [7.9, 15.0]	0.633
NFS index	-2.2 [-3.5, -1.3]	-2.1 [-3.7, -0.9]	-2.3 [-3.5, -1.5]	0.493
ALP (U/L)	87 [70, 129]	101 [79, 195]	86 [69, 118]	0.128

ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; DGE: Delayed gastric emptying; FIB-4: Fibrosis-4; LDPPHRt: Laparoscopic duodenum-preserving total pancreatic head resection; LPD: Laparoscopic pancreaticoduodenectomy; NAFLD: Nonalcoholic fatty liver disease; POPF: Postoperative pancreatic fistula; SSI: Surgical site infection; TBIL: Total bilirubin; NFS: Nonalcoholic fatty liver disease fibrosis score.