Helicobacter pylori infection is linked to metabolic dysfunction and associated steatotic liver disease: A large cross-sectional study

Table 1 Comparison of clinical data between Helicobacter pylori-positive and Helicobacter pylori-negative groups

Parameter	H. pylori-negative group (n = 20946)	H. pylori-positive group (n = 7678)	t value	P value
Age (years)	46 ± 14.86	46.43 ± 14.45	2.443	0.015
Blood glucose (mmol/L)	5.27 ± 1.23	5.43 ± 1.55	-7.79	0.001
HDL (mmol/L)	1.41 ± 0.37	1.38 ± 0.37	4.23	0.001
Total cholesterol (mmol/L)	4.85 ± 0.97	4.88 ± 0.99	-2.37	0.018
Triglycerides (mmol/L)	1.62 ± 1.48	1.65 ± 1.48	-1.61	0.107
LDL (mmol/L)	2.94 ± 0.75	2.97 ± 0.76	-3.2	0.001
BMI (kg/m²)	23.64 ± 3.35	23.89 ± 3.46	-5.3	0.001
Systolic blood pressure (mmHg)	122.85 ± 18.33	123.49 ± 19.06	-2.57	0.009
Diastolic blood pressure (mmHg)	74.9 ± 11.9	75.48 ± 12.37	-3.53	0.001
Gender (male/female)	11803/9143	4258/3420	χ2 = 1.821	0.179
MASLD detection rate	7424/13522	2845/4833	χ2 = 6.331	0.012

¹The test method for this item is the χ² test.

Data are presented as mean ± SD or n (%). Continuous variables were analyzed via the Student’s t-test; categorical variables were analyzed via the χ² test. H. pylori: Helicobacter pylori; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; BMI: Body mass index; MASLD: Metabolic dysfunction-associated steatotic liver disease.