Suppressor of cytokine signaling 2 modulates regulatory T cell activity to suppress liver hepatocellular carcinoma growth and metastasis

Figure 4 Molecular characteristics revealing prognostic genes of liver hepatocellular carcinoma. A: Survival curves of ABCA8, CCL25, APCDD1, SELP, and suppressor of cytokine signaling 2 (SOCS2) in The Cancer Genome Atlas (TCGA)-Liver hepatocellular carcinoma (LIHC) dataset; B: Expression boxplots of ABCA8, CCL25, SELP, and SOCS2 in the TCGA-LIHC dataset, with ^cP < 0.001; C: Correlation analysis between ABCA8 and regulatory T-cell (Treg) cells; D: Correlation analysis between SOCS2 and Treg cells. Control, n = 50; LIHC, n = 373. SOCS2: Suppressor of cytokine signaling 2; Treg: Regulatory T-cell; HR: Hazard ratio.