Suppressor of cytokine signaling 2 modulates regulatory T cell activity to suppress liver hepatocellular carcinoma growth and metastasis

Figure 2 Molecular mechanism of regulatory T-cell infiltration in liver hepatocellular carcinoma. A: Scale independence (left) and average connectivity (right) to determine the weighted value β = 4 that satisfies the scale-free network law; B: Dendrogram of co-expression network modules; C: Heatmap showing the correlation between 35 modules; D: Correlation analysis between modules and high or low regulatory T-cell (Treg) cell infiltration; E: Scatter plots analyzing the relationship between the brown, red, blue, saddle brown, and pink modules and Treg-High infiltration. Liver hepatocellular carcinoma, n = 373.