Involvement of the NLRP3/IL-1β pathway in activation and effector functions of γδT17 cells in patients with ulcerative colitis

Figure 5 The expression levels of NLR family pyrin domain containing 3, apoptosis-associated speck-like protein, caspase-1 and interleukin-1β in colonic mucosal tissues. NLR family pyrin domain containing 3, apoptosis-associated speck-like protein, caspase-1, and IL-1β are widely expressed in cytoplasm and their expression levels were elevated to different extents in colonic mucosal tissues of ulcerative colitis patients. ^aP < 0.05, ^bP < 0.01 vs healthy control (magnification: 200 ×). NLRP3: NLR family pyrin domain containing 3; ASC: Apoptosis-associated speck-like protein; IL: Interleukin; UC: Ulcerative colitis; IOD: Integrated optical density.