Involvement of the NLRP3/IL-1β pathway in activation and effector functions of γδT17 cells in patients with ulcerative colitis

Figure 3 Levels of serum inflammatory factors in healthy controls and ulcerative colitis patients. A: Interleukin-21 (IL-21); B: IL-22; C: IL-23 were significantly elevated; D: tumor necrosis factor α; E: Granulocyte-macrophage colony stimulating factor; F: IL-17; G: IL-18; H: IL-1β were significantly elevated; I: Anti-inflammatory cytokines transforming growth factor β were decreased; J: Anti-inflammatory cytokines IL-10 were decreased. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs healthy control. UC: Ulcerative colitis; IL: Interleukin; TNF-α: Tumor necrosis factor α; GM-CSF: Granulocyte-macrophage colony stimulating factor; TGF-β: Transforming growth factor β.