Increased keratin 80 expression predicts poor prognosis and promotes oxaliplatin resistance in gastric cancer

Figure 5 Keratin 80 promotes oxaliplatin resistance in gastric cancer cells by activating NF-κB signaling pathway. A: Schematic diagram illustrating the experimental design for the animal studies; B: Representative images of dissected xenografts from the indicated groups at the conclusion of the experiment; C and D: Tumor weights and growth curves of subcutaneous xenografts from the indicated experimental groups; E: Western blot analysis was performed to evaluate the expression of key proteins involved in the NF-κB signaling pathway and apoptosis regulation. Data are shown as the mean ± SD (n = 3). ^aP < 0.05; ^bP < 0.05; ^cP < 0.001; KRT80: Keratin 80; Bcl-2: B-cell lymphoma-2.