Increased keratin 80 expression predicts poor prognosis and promotes oxaliplatin resistance in gastric cancer

Figure 3 Knockdown of keratin 80 expression suppresses tumor growth in mouse xenograft model. A: Tumor volumes were measured at the indicated time points for each experimental group; B: After euthanasia, tumors were excised from the mice, and the weight of each tumor was recorded; C: Western blot analysis was performed to evaluate the expression levels of keratin 80, B-cell lymphoma-2 (Bcl-2), BCL-XL, MCL-1, Bcl-2-associated X protein, and BAD in subcutaneous tumor samples from AGS and SGC7901 cells in each treatment group. Data are shown as the mean ± SD (n = 3). ^aP < 0.05; ^bP < 0.05; ^cP < 0.001; KRT80: Keratin 80; Bcl-2: B-cell lymphoma-2.