Increased keratin 80 expression predicts poor prognosis and promotes oxaliplatin resistance in gastric cancer

Figure 2 The expression level of keratin 80 affects the gastric cancer cells malignant phenotypes. A and B: Western blot analysis and quantitative real-time PCR were employed to confirm the overexpression and knockdown efficiency of keratin 80 (KRT80) in the gastric cancer (GC) cells; C: The effect of KRT80 overexpression or knockdown on GC cell proliferation was assessed using cell growth curve analysis; D: Transwell assays were performed to evaluate the migratory and invasive capabilities of GC cells with stable overexpression or knockdown of KRT80. Data are shown as the mean ± SD (n = 3). ^aP < 0.05; ^bP < 0.05; ^cP < 0.001; KRT80: Keratin 80.