Basic Study
Copyright ©The Author(s) 2025.
World J Gastroenterol. Mar 28, 2025; 31(12): 103991
Published online Mar 28, 2025. doi: 10.3748/wjg.v31.i12.103991
Table 2 Univariate and multivariate analysis of clinicopathological variables and keratin 80 expression associated with overall survival
Parameters
Univariate analysis
Multivariate analysis
HR (95%CI)
P value
HR (95%CI)
P value
Gender (male vs female)1.230 (0.682-2.216)0.491
Age (< 60 years vs ≥ 60 years)1.475 (0.834-2.609)0.181
Tumor location (upper vs middle + lower)0.827 (0.468-1.462)0.514
Tumor size (< 6 cm vs ≥ 6 cm)0.879 (0.501-1.544)0.653
Differentiation (well + moderate vs poor + undifferentiated)0.758 (0.432-1.330)0.335
pT stage (T1-T2 vs T3-T4 )1.047 (0.597-1.836)0.872
Lymph node metastasis (absent vs present)3.212 (1.155-8.938)0.0253.110 (1.117-8.657)0.03
pTNM stage (I-II vs III-IV)1.409 (0.703-2.842)0.333
KRT80 expression (low vs high)2.174 (1.169-4.044)0.0142.119 (1.139-3.943)0.018