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©The Author(s) 2025.
World J Gastroenterol. Mar 28, 2025; 31(12): 103991
Published online Mar 28, 2025. doi: 10.3748/wjg.v31.i12.103991
Published online Mar 28, 2025. doi: 10.3748/wjg.v31.i12.103991
Table 2 Univariate and multivariate analysis of clinicopathological variables and keratin 80 expression associated with overall survival
Parameters | Univariate analysis | Multivariate analysis | ||
HR (95%CI) | P value | HR (95%CI) | P value | |
Gender (male vs female) | 1.230 (0.682-2.216) | 0.491 | ||
Age (< 60 years vs ≥ 60 years) | 1.475 (0.834-2.609) | 0.181 | ||
Tumor location (upper vs middle + lower) | 0.827 (0.468-1.462) | 0.514 | ||
Tumor size (< 6 cm vs ≥ 6 cm) | 0.879 (0.501-1.544) | 0.653 | ||
Differentiation (well + moderate vs poor + undifferentiated) | 0.758 (0.432-1.330) | 0.335 | ||
pT stage (T1-T2 vs T3-T4 ) | 1.047 (0.597-1.836) | 0.872 | ||
Lymph node metastasis (absent vs present) | 3.212 (1.155-8.938) | 0.025 | 3.110 (1.117-8.657) | 0.03 |
pTNM stage (I-II vs III-IV) | 1.409 (0.703-2.842) | 0.333 | ||
KRT80 expression (low vs high) | 2.174 (1.169-4.044) | 0.014 | 2.119 (1.139-3.943) | 0.018 |
- Citation: Yang B, Cao HX, He YW, Ouyang JJ, Lv M, Li YX, Lu YD. Increased keratin 80 expression predicts poor prognosis and promotes oxaliplatin resistance in gastric cancer. World J Gastroenterol 2025; 31(12): 103991
- URL: https://www.wjgnet.com/1007-9327/full/v31/i12/103991.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i12.103991