Characterization of hepatic pathology during azoxymethane-induced acute liver failure

Figure 6 Azoxymethane induces changes to liver necroptosis signaling. A: Immunohistochemistry images for pMLKL in livers from vehicle- and azoxymethane (AOM)-treated mice at pre, minor, major and coma time points; B and C: Representative immunoblot and quantification of pMLKL protein immunoblots in liver homogenates from mice administered vehicle or AOM at the pre, minor, major and coma time points. GAPDH was used as a protein loading control. n ≥ 3 for each group for all analyses. ^aP < 0.05 compared to vehicle-treated mice.